Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770370 | 0.87 | BACE1 (0.53) | LMNABACE1ABCB1PPARDALDH1A1 | |
| SCHEMBL9770474 | 0.86 | BACE1 (0.62) | BACE1PPARD | |
| SCHEMBL9770393 | 0.85 | MAPT (0.64) | MAPTLMNAPOLBNPSR1BACE1 | |
| SCHEMBL9770331 | 0.85 | BACE1 (0.52) | POLBBACE1PPARDALDH1A1 | |
| SCHEMBL9770507 | 0.85 | BACE1 (0.52) | LMNABACE1PPARD | |
| SCHEMBL9770448 | 0.83 | BACE1 (0.59) | MAPTLMNABACE1PPARD | |
| SCHEMBL9770497 | 0.83 | NPC1 (0.57) | MAPTBACE1PPARDALDH1A1 | |
| SCHEMBL9770535 | 0.81 | BACE1 (0.57) | MAPTLMNABACE1PPARDMAOB | |
| SCHEMBL9770581 | 0.80 | ALDH1A1 (0.48) | MAPTLMNAPOLBBACE1ALDH1A1 | |
| SCHEMBL9770514 | 0.77 | CA1 (0.45) | LMNABACE1MAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |