Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770570 | 0.85 | BACE1 (0.76) | BACE1SMN1; SMN2POLBRAB9AKDM4E | |
| SCHEMBL9770444 | 0.85 | BACE1 (0.64) | BACE1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9480490 | 0.84 | BACE1 (0.80) | BACE1RAB9AKDM4ECYP2C19 | |
| SCHEMBL9770536 | 0.83 | BACE1 (0.62) | BACE1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9770321 | 0.82 | BACE1 (0.76) | BACE1SMN1; SMN2KDM1ARAB9A | |
| SCHEMBL9770465 | 0.82 | BACE1 (0.76) | BACE1SMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL9770389 | 0.82 | BACE1 (0.64) | BACE1 | |
| SCHEMBL9770232 | 0.82 | BACE1 (0.64) | BACE1SMN1; SMN2KDM4E | |
| SCHEMBL9770439 | 0.81 | BACE1 (0.60) | BACE1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9770406 | 0.81 | BACE1 (0.60) | BACE1SMN1; SMN2POLBHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |