Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | CCR3 | P51677 | 3/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770536 | 0.84 | BACE1 (0.62) | BACE1PRMT5WDR77HSD17B10KMT2A | |
| SCHEMBL9480490 | 0.83 | BACE1 (0.80) | BACE1HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL9770570 | 0.81 | BACE1 (0.76) | BACE1HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL9770148 | 0.81 | BACE1 (0.58) | BACE1HSD17B10KMT2ARAB9AMAPK1 | |
| SCHEMBL9770438 | 0.81 | TSHR (0.59) | BACE1MAPK1TSHRHIF1AL3MBTL1 | |
| SCHEMBL9770455 | 0.81 | BACE1 (0.58) | BACE1PRMT5WDR77HSD17B10KMT2A | |
| SCHEMBL9770402 | 0.81 | BACE1 (0.58) | BACE1KMT2AMAPK1TSHRHIF1A | |
| SCHEMBL9770232 | 0.80 | BACE1 (0.64) | BACE1PRMT5WDR77HSD17B10KMT2A | |
| SCHEMBL9770389 | 0.80 | BACE1 (0.64) | BACE1PRMT5WDR77HSD17B10KMT2A | |
| SCHEMBL9770465 | 0.78 | BACE1 (0.76) | BACE1HSD17B10KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |