SCHEMBL9770516

SCHEMBL9770516

CCCCc1cc(OO)ccc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.41
HTT P42858 2/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LTA4H P09960 3/20 0.37
TSHR P16473 2/20 0.36
SKP2 Q13309 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
CYP3A4 P08684 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TP53 P04637 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10357434 0.89 TAAR1 (0.37) LTA4HTSHRTAAR1CYP3A4ALOX5
SCHEMBL5859433 0.81 TYR (0.38) TYRHTTNPC1HPGDMAPK1
SCHEMBL11532417 0.81 SMN1; SMN2 (0.40) NPC1MAPK1TP53TDP1ALDH1A1
SCHEMBL23153214 0.79 PTGS2 (0.44) TAAR1ALOX5TDP1
SCHEMBL7559321 0.78 TYR (0.38) TYRHTTNPC1HPGDMAPK1
SCHEMBL14583346 0.77 CNR2 (0.50) MAPK1TSHRCYP3A4MEN1KMT2A
SCHEMBL28235163 0.77 MAOA (0.40) HPGDMAPK1TSHRMEN1KMT2A
SCHEMBL27715804 0.77 THRB (0.57) NPC1HPGDTSHRMEN1KMT2A
SCHEMBL5859441 0.76 LIPG (0.45) TYRHTTMAPK1TSHRCYP3A4
SCHEMBL5858851 0.76 LIPG (0.45) TYRHTTMAPK1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3011058-A None JP disclosed
JP-H0311058-A PRODUCTION OF SEC-BUTYLTOLUENE HYDROPEROXIDE MITSUI PETROCHEM IND LTD 1991-01-18 JP disclosed