Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770634 | 0.74 | LMNA (0.53) | CTSBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL9059478 | 0.74 | CTSB (0.56) | CTSBLMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL9770618 | 0.73 | CTSB (0.53) | CTSBLMNAMAPTPOLBHTT | |
| SCHEMBL9770553 | 0.72 | LMNA (0.51) | LMNAMAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL30307430 | 0.71 | NCF1 (0.67) | CTSBPTK2MAPTPOLBALDH1A1 | |
| SCHEMBL3836532 | 0.71 | NCF1 (0.67) | CTSBPTK2MAPTPOLBALDH1A1 | |
| SCHEMBL4702680 | 0.71 | CTSB (0.45) | CTSBLMNAPTK2MAPTPOLB | |
| SCHEMBL9770560 | 0.71 | ALDH1A1 (0.54) | LMNAMAPTHTTALDH1A1HPGD | |
| SCHEMBL4871412 | 0.71 | CTSB (1.00) | CTSBLMNAMAPTPOLBHTT | |
| SCHEMBL8561101 | 0.70 | POLB (0.53) | MAPTPOLBHTTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019574-A | 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | disclosed |