Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 12/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30779614 | 1.00 | CTSB (0.68) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL3435076 | 0.94 | CTSB (0.65) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL1274938 | 0.87 | HTT (0.73) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL3435490 | 0.85 | CTSB (0.52) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL1124142 | 0.84 | CASP1 (0.56) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL1124008 | 0.84 | CASP1 (0.56) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL16943039 | 0.84 | CTSB (0.57) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL3651950 | 0.84 | CTSB (0.57) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL27888685 | 0.84 | CTSB (0.57) | CTSBALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL3799173 | 0.84 | CTSB (0.65) | CTSBALDH1A1CYP1A2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108339551-A | A kind of preparation method of novel antibacterial medicine linezolid intermediate | 邵宏超 | 2018-07-31 | — | — | CN | claimed |
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-12-22 | — | — | US | claimed |
| WO-2010097815-A2 | A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | claimed |
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| US-11479528-B2 | Heat shock protein 90 inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-10-25 | — | — | US | disclosed |
| CN-111164074-A | Heat shock protein 90 inhibitor | 台北医学大学 | 2020-05-15 | — | — | CN | disclosed |
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-02-06 | — | — | US | disclosed |
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170002005-A1 | Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins | LIFE MOLECULAR IMAGING LIMITED (GB) | 2017-01-05 | — | — | US | disclosed |
| US-20170002005-A1 | Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins | LIFE MOLECULAR IMAGING LIMITED (GB) | 2017-01-05 | — | — | US | disclosed |
| US-4168151-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |
| US-4153443-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4133673-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133672-A | (Aminophenyl)morpholines and use thereof | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4126442-A | O-Phosphoroamidophenylmorpholine compounds and use as herbicides | UNITED STATES BORAX & CHEMICAL CORP. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4123251-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
| US-4094663-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1978-06-13 | — | — | US | disclosed |
| US-4094662-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1978-06-13 | — | — | US | disclosed |
| US-4049422-A | Herbicidal morpholinobenzimidazoles | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | CTSB 3436/4885ALDH1A1 1138/4885CYP1A2 3098/4885 |
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | HCN2, RAC2, HCN1 | CTSB 3248/4885ALDH1A1 1225/4885CYP1A2 430/4885 |
| US-11479528-B2 | Heat shock protein 90 inhibitors | HSP90AB1, HSP90AB2P, HSP90AA1 | CTSB 3436/4885ALDH1A1 1138/4885CYP1A2 3098/4885 |
| US-20170002005-A1 | Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins | APP, BACE1, PSEN1 | CTSB 421/4885ALDH1A1 2201/4885CYP1A2 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.