Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866370 | 0.70 | HTT (0.39) | HTTKMT2AALDH1A1GAATSHR | |
| SCHEMBL6538562 | 0.68 | HTR2A (0.44) | — | |
| SCHEMBL9770756 | 0.61 | RXRA (0.41) | HTTKMT2AALDH1A1 | |
| SCHEMBL29518297 | 0.61 | RXRA (0.41) | HTTKMT2AALDH1A1 | |
| SCHEMBL7622765 | 0.59 | RXRA (0.48) | KMT2A | |
| Methane SCHEMBL28424227 | 0.59 | HTT (0.38) | HTTKMT2AALDH1A1GAATSHR | |
| SCHEMBL7928546 | 0.58 | HTT (0.36) | HTTALDH1A1GAATSHR | |
| SCHEMBL6905998 | 0.57 | MAPT (0.45) | HTTKMT2AALDH1A1GAATSHR | |
| SCHEMBL7188472 | 0.57 | HTT (0.36) | HTTKMT2AALDH1A1GAATSHR | |
| SCHEMBL29232865 | 0.57 | HTT (0.40) | HTTKMT2AALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987261-A | Diaminoindane derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-01-22 | — | — | US | claimed |