Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PPIA | P62937 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770719 | 0.92 | MEN1 (0.69) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL9770823 | 0.91 | MEN1 (0.71) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL9770798 | 0.90 | MEN1 (0.70) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL1207169 | 0.83 | ALDH1A1 (0.71) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL9770834 | 0.77 | MEN1 (0.55) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL7800011 | 0.76 | CTSD (0.56) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL4468688 | 0.76 | CTSD (0.64) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL13753116 | 0.76 | CTSD (0.64) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL13753006 | 0.75 | CTSD (0.68) | LMNAMEN1KMT2AKDM4ECTSD | |
| SCHEMBL11298067 | 0.75 | ALDH1A1 (0.72) | LMNAMEN1KMT2AKDM4ECTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987135-A | Leukemia, melanoma | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-01-22 | — | — | US | claimed |