Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | ALPL | P05186 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451182 | 0.80 | ALDH1A1 (0.71) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9763219 | 0.79 | CTSD (0.70) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL962966 | 0.78 | CTSD (1.00) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11298067 | 0.78 | ALDH1A1 (0.72) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL296470 | 0.76 | ALDH1A1 (0.76) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL31621278 | 0.76 | ALDH1A1 (0.76) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6971514 | 0.76 | ALDH1A1 (0.76) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL4543254 | 0.76 | CTSD (0.66) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9770714 | 0.76 | LMNA (0.65) | CTSDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10602289 | 0.76 | CTSD (0.70) | CTSDALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625917-B2 | S-o-(phenylaminocarbonyl)phenyl-substituted, especially with a quaternary onium group; enhanced antiviral activity and better reactivity with zinc finger moieties, particularly, the zinc finger on HIV-1's NCp7 nucleocapsid protein | TURPIN JAMES A | 2009-12-01 | — | — | US | disclosed |
| EP-1087941-B9 | THIOLESTERS AND USES THEREOF | US HEALTH (US) | 2007-11-07 | — | — | EP | disclosed |
| EP-1087941-B1 | THIOLESTERS AND USES THEREOF | US HEALTH (US) | 2006-08-16 | — | — | EP | disclosed |
| US-20040132785-A1 | Thiolesters and uses thereof | The Government of the U. S.of America as Represented by The Sec. of Health and Human Svc. (US) | 2004-07-08 | — | — | US | disclosed |
| EP-1087941-A2 | THIOLESTERS AND USES THEREOF | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065871-A2 | THIOLESTERS AND USES THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132785-A1 | Thiolesters and uses thereof | SARS1, HAVCR2, P4HB | CTSD 2174/4885ALDH1A1 552/4885MEN1 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.