Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770823 | 0.96 | MEN1 (0.71) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9770798 | 0.95 | MEN1 (0.70) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9770714 | 0.92 | LMNA (0.65) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9770834 | 0.80 | MEN1 (0.55) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9439969 | 0.78 | KMT2A (0.56) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL4960015 | 0.77 | HTT (0.69) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28194182 | 0.76 | MEN1 (0.58) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL1207169 | 0.76 | ALDH1A1 (0.71) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL5508331 | 0.76 | HTT (0.62) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9172165 | 0.75 | NAAA (0.63) | MEN1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987135-A | Leukemia, melanoma | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-01-22 | — | — | US | claimed |