Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199131 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SRD5A2KDM4EMAPTCA12 | |
| SCHEMBL27767108 | 0.80 | TRPA1 (0.57) | ALDH1A1KDM4EMAPTCA12CA1 | |
| SCHEMBL7400636 | 0.77 | TDP2 (0.50) | ALDH1A1SRD5A2KDM4EMAPTCA12 | |
| SCHEMBL4024917 | 0.74 | ALDH1A1 (0.43) | ALDH1A1SRD5A2KDM4EMAPTCA12 | |
| SCHEMBL7001972 | 0.74 | SRD5A2 (0.46) | ALDH1A1SRD5A2KDM4EMAPTPOLB | |
| SCHEMBL25171204 | 0.71 | ALDH1A1 (0.49) | ALDH1A1SRD5A2KDM4EMAPTCA12 | |
| SCHEMBL9770840 | 0.70 | PTPN1 (0.44) | ALDH1A1KDM4EMAPTKDM6BTET3 | |
| SCHEMBL29790265 | 0.70 | KDM4E (0.41) | ALDH1A1KDM4EMAPTCA12CA1 | |
| SCHEMBL8369280 | 0.70 | ALDH1A1 (0.50) | ALDH1A1SRD5A2KDM4EMAPTCA12 | |
| SCHEMBL1239354 | 0.70 | HTT (0.42) | ALDH1A1KDM4EMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427632-B2 | Factor Xa inhibitors | ELI LILLY AND COMPANY (US) | 2008-09-23 | — | — | US | disclosed |
| US-20060052606-A1 | Factor xa Inhibitors | ELI LILLY AND COMPANY | 2006-03-09 | — | — | US | disclosed |
| EP-1581493-A1 | FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004060872-A1 | FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052606-A1 | Factor xa Inhibitors | F12, F11, SERPINC1 | ALDH1A1 3097/4885SRD5A2 553/4885KDM4E 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.