Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770829 | 0.92 | ADRB2 (0.38) | ADRB2ADRB1ADRB3AVPR1BHRH3 | |
| SCHEMBL9770814 | 0.91 | GLA (0.40) | ADRB2ADRB1ADRB3AVPR1BHRH3 | |
| SCHEMBL9770894 | 0.90 | AVPR1B (0.38) | ADRB2ADRB1ADRB3AVPR1BHRH3 | |
| SCHEMBL9770796 | 0.87 | ADRB2 (0.37) | ADRB2ADRB1ADRB3AVPR1BHRH3 | |
| SCHEMBL9770835 | 0.84 | SLC2A1 (0.35) | ADRB2ADRB1ADRB3AVPR1BHRH3 | |
| SCHEMBL9770892 | 0.84 | AVPR1B (0.38) | ADRB1ADRB3AVPR1BHRH3DRD4 | |
| SCHEMBL9770964 | 0.83 | SLC5A2 (0.35) | AVPR1BHRH3DRD4LMNAPPARG | |
| SCHEMBL9251458 | 0.83 | PIK3CA (0.38) | ADRB2ADRB1ADRB3PIK3CAAVPR1B | |
| SCHEMBL9770815 | 0.82 | HRH3 (0.42) | HRH3 | |
| SCHEMBL9770885 | 0.81 | HRH3 (0.35) | HRH3DRD4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | disclosed |
| EP-0334146-A1 | Morpholines and morpholine-N-oxides, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |