Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | LTA4H | P09960 | 7/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770796 | 0.88 | ADRB2 (0.37) | HRH3 | |
| SCHEMBL9770964 | 0.86 | SLC5A2 (0.35) | HRH3ACACB | |
| SCHEMBL9770835 | 0.85 | SLC2A1 (0.35) | HRH3 | |
| SCHEMBL9770885 | 0.83 | HRH3 (0.35) | HRH3LTA4H | |
| SCHEMBL9770829 | 0.83 | ADRB2 (0.38) | HRH3 | |
| SCHEMBL9770863 | 0.82 | ADRB2 (0.39) | HRH3 | |
| SCHEMBL9770814 | 0.81 | GLA (0.40) | HRH3 | |
| SCHEMBL8880830 | 0.81 | LTA4H (0.39) | HRH3LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL9770894 | 0.81 | AVPR1B (0.38) | HRH3 | |
| SCHEMBL9770892 | 0.78 | AVPR1B (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | disclosed |