Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770885 | 0.90 | HRH3 (0.35) | HRH3DRD4PPARGPPARAMEN1 | |
| SCHEMBL9770796 | 0.89 | ADRB2 (0.37) | HRH3DRD4PPARGPPARASIGMAR1 | |
| SCHEMBL9770835 | 0.87 | SLC2A1 (0.35) | HRH3DRD4PPARGPPARASIGMAR1 | |
| SCHEMBL9770815 | 0.86 | HRH3 (0.42) | HRH3ACACB | |
| SCHEMBL8881216 | 0.86 | HRH3 (0.35) | SLC5A2HRH3DRD4ACACBPPARG | |
| SCHEMBL9770829 | 0.84 | ADRB2 (0.38) | HRH3DRD4PPARGPPARAAVPR1B | |
| SCHEMBL9770863 | 0.83 | ADRB2 (0.39) | HRH3DRD4PPARGPPARAAVPR1B | |
| SCHEMBL9770814 | 0.83 | GLA (0.40) | HRH3DRD4AVPR1BMEN1LMNA | |
| SCHEMBL9770894 | 0.82 | AVPR1B (0.38) | HRH3AVPR1BMEN1LMNAKMT2A | |
| SCHEMBL9825901 | 0.80 | ACACB (0.32) | HRH3ACACBPPARGPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | disclosed |
| EP-0334146-A1 | Morpholines and morpholine-N-oxides, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |