Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.52 |
| ▸ | METAP1 | P53582 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521376 | 1.00 | METAP2 (0.52) | METAP2METAP1ALDH1A1MEN1KMT2A | |
| SCHEMBL10521370 | 1.00 | METAP2 (0.52) | METAP2METAP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7300559 | 0.87 | MEN1 (0.52) | METAP2METAP1ALDH1A1MEN1KMT2A | |
| SCHEMBL6647029 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACTSBCTSS | |
| SCHEMBL6476379 | 0.82 | METAP2 (0.64) | METAP2METAP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3320858 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ACTSBCTSS | |
| SCHEMBL2541204 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ACTSBCTSS | |
| SCHEMBL12135341 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8269724 | 0.81 | CTSK (0.57) | METAP2METAP1ALDH1A1CTSBCTSS | |
| SCHEMBL1863093 | 0.81 | CTSK (0.57) | METAP2METAP1ALDH1A1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045537-A | Treating Diseases Caused by Retroviruses | SANDOZ LTD. (CH) | 1991-09-03 | — | — | US | disclosed |
| EP-0255082-A2 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |