Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485382 | 0.79 | ALDH1A1 (0.41) | MAPTCYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL10429606 | 0.74 | L3MBTL1 (0.47) | MAPTCYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL10915365 | 0.73 | MEN1 (0.46) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1483825 | 0.71 | ABL1 (0.43) | MAPTCYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL9824583 | 0.70 | KMT2A (0.38) | MAPTCYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL9824588 | 0.70 | KMT2A (0.38) | MAPTCYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL8484111 | 0.69 | ALDH1A1 (0.42) | MAPTCYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL9430928 | 0.68 | TSHR (0.42) | MAPTCYP3A4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL26968324 | 0.68 | MAPT (0.45) | MAPTCYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL9430923 | 0.68 | RAD51 (0.38) | MAPTCYP3A4KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0304920-A2 | Condensed heterocyclic derivatives, process for their production and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |