SCHEMBL9770937

SCHEMBL9770937

Cc1ccc2c(c1Cl)C(=O)N(C1(C#N)CCCCC1)C2=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 1/20 0.31
GAA P10253 1/20 0.31
ALOX12 P18054 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11727273 0.78 NSD2 (0.36) PDE7ASMN1; SMN2
SCHEMBL9770940 0.75 ALDH1A1 (0.36) PDE7AGAA
SCHEMBL11722347 0.75 ALDH1A1 (0.41) ALOX12SMN1; SMN2
SCHEMBL11731108 0.66 ALDH1A1 (0.34)
SCHEMBL10648688 0.63
SCHEMBL9845547 0.61 CYP2C19 (0.60) GAASMN1; SMN2
SCHEMBL19382151 0.58 PDE7A (0.37) PDE7ASMN1; SMN2
SCHEMBL13093582 0.57 MAOA (0.42) GAASMN1; SMN2
SCHEMBL26828627 0.57 BRD4 (0.38) GAA
SCHEMBL29691017 0.56 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5073190-A Substituted phthalimido cyclohexanecarboxamides and compositions thereof for enhancing growth of hybrid tea rose plants AMERICAN CYANAMID COMPANY (US) 1991-12-17 US disclosed
US-5019154-A Plant growth regulators AMERICAN CYANAMID COMPANY (US) 1991-05-28 US disclosed
EP-0427907-A2 Substituted phthalimido cyclohexanecarboxamides and the use thereof for enhancing growth of hybrid tea rose plants AMERICAN CYANAMID COMPANY (US) 1991-05-22 EP disclosed