SCHEMBL97716

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8943857	0.84	ALDH1A1 (0.46)	KMT2ASMN1; SMN2PNMTTAAR1PTGS2
	SCHEMBL97464	0.81	PNMT (0.54)	KMT2ASMN1; SMN2PNMTTAAR1ALDH1A1
	SCHEMBL5255980	0.81	ALDH1A1 (0.36)	KMT2ASMN1; SMN2MEN1ALDH1A1POLB
	SCHEMBL2701205	0.81	PNMT (0.37)	MCL1KMT2ASMN1; SMN2S1PR1KDM4A
	SCHEMBL10946217	0.80	PTPN7 (0.37)	MCL1KMT2ASMN1; SMN2S1PR1KDM4A
	SCHEMBL7200049	0.80	ENPP2 (0.38)	MCL1S1PR1KDM4AKDM5AKDM5B
	SCHEMBL2785762	0.78	DAO (0.45)	PTGS2PTPN7DUSP3PTGS1
	SCHEMBL14465785	0.77	S1PR1 (0.37)	MCL1KMT2ASMN1; SMN2S1PR1KDM4A
	SCHEMBL3022192	0.77	MCL1 (0.42)	MCL1KMT2ASMN1; SMN2S1PR1KDM4A
	SCHEMBL11699828	0.76	SKP2 (0.52)	KMT2ASMN1; SMN2MEN1ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.