Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325853 | 0.83 | SMN1; SMN2 (0.37) | GAAALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9772563 | 0.81 | ALDH1A1 (0.44) | GAAL3MBTL1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL9772462 | 0.79 | HSD17B10 (0.40) | GAASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL9772437 | 0.78 | RAB9A (0.44) | GAAL3MBTL1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL9772745 | 0.77 | KDM4E (0.51) | GAAL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9772459 | 0.77 | PTGS2 (0.38) | GAASMN1; SMN2MAPTCYP17A1NPC1 | |
| SCHEMBL28866207 | 0.74 | SMN1; SMN2 (0.47) | GAASMN1; SMN2MAPTPDE10ACYP17A1 | |
| SCHEMBL13178571 | 0.74 | KDM4E (0.34) | GAAALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28052152 | 0.68 | SMN1; SMN2 (0.46) | GAASMN1; SMN2MAPTPDE10ANPC1 | |
| SCHEMBL9772626 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041442-A | Antiulcer agents | SYNTEX (U.S.A.) INC. (US) | 1991-08-20 | — | — | US | disclosed |