Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772462 | 0.83 | HSD17B10 (0.40) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9772563 | 0.82 | ALDH1A1 (0.44) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9772837 | 0.81 | RORB (0.43) | GAAIDO1TDO2ADORA1 | |
| SCHEMBL9772745 | 0.78 | KDM4E (0.51) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9772459 | 0.78 | PTGS2 (0.38) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9772463 | 0.78 | GAA (0.38) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3042386 | 0.75 | KDM4E (0.33) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7317792 | 0.74 | ALDH1A3 (0.54) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9772460 | 0.72 | CYP11B1 (0.38) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL4691850 | 0.71 | PDE3B (0.47) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041442-A | Antiulcer agents | SYNTEX (U.S.A.) INC. (US) | 1991-08-20 | — | — | US | disclosed |