SCHEMBL977348

SCHEMBL977348

CC(=O)c1ccc2c(CN(CCCCCCN)Cc3ccccc3B(O)O)c3ccccc3c(CN(CCCCCCN)Cc3ccccc3B(O)O)c2c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
POLB P06746 1/20 0.33
HTR1A P08908 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
MAPT P10636 1/20 0.33
MC4R P32245 9/20 0.33
MC5R P33032 9/20 0.33
MC3R P41968 8/20 0.33
MC1R Q01726 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21191985 1.00 ACHE (0.34) ACHEALDH1A1HPGDPOLBHTR1A
SCHEMBL21191986 0.93 ACHE (0.31) ACHE
SCHEMBL974905 0.89 ACHE (0.37) ACHEALDH1A1MC4RMC5RMC3R
SCHEMBL30443493 0.88 MC4R (0.37) ACHEHTR1AHTR1DHTR1BMC4R
SCHEMBL976168 0.87 LIPG (0.40) ACHEMC4RMC5RMC3RLIPG
SCHEMBL20081108 0.86 MC4R (0.31) MC4RMC5RMC3R
SCHEMBL21191987 0.79 ACHE (0.30) ACHE
SCHEMBL20926054 0.79 MAPT (0.36) ALDH1A1HPGDPOLBMAPT
SCHEMBL20320676 0.76 TMEM97 (0.33) ALDH1A1HPGD
SCHEMBL12922751 0.72 ZDHHC20 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822722-B2 Fluorescent hydrogel and method for producing the same, and sensor for measuring saccharides using the same TERUMO KABUSHIKI KAISHA (JP) 2014-09-02 US disclosed
US-8822722-B2 Fluorescent hydrogel and method for producing the same, and sensor for measuring saccharides using the same TERUMO KABUSHIKI KAISHA (JP) 2014-09-02 US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 US disclosed
US-7873398-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2011-01-18 US disclosed
US-7524985-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2009-04-28 US disclosed
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-12-25 US disclosed
US-7388110-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-06-17 US disclosed
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-01-24 US disclosed
EP-1619229-B1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO CORP (JP) 2007-04-11 EP disclosed
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA 2006-01-26 US disclosed
EP-1619229-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2006-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ACHE 2236/4885ALDH1A1 167/4885HPGD 442/4885
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ACHE 2139/4885ALDH1A1 273/4885HPGD 632/4885
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ACHE 2139/4885ALDH1A1 273/4885HPGD 632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.