Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 5/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | DRD4 | P21917 | 4/20 | 0.56 |
| ▸ | DRD5 | P21918 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576519 | 0.81 | L3MBTL1 (0.63) | HRH1HPGDSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL5249495 | 0.81 | HRH1 (0.66) | HRH1HPGDSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL7089438 | 0.81 | LTB4R (0.55) | SMN1; SMN2CYP2C9TSHRLMNA | |
| SCHEMBL1115043 | 0.80 | LMNA (0.56) | SMN1; SMN2LMNAKDM4E | |
| SCHEMBL19733216 | 0.80 | HPGD (0.67) | HRH1HPGDSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL4350513 | 0.80 | HPGD (0.67) | HRH1HPGDSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL7087899 | 0.79 | LTB4R (0.54) | HRH1HPGDSMN1; SMN2CYP2C9TSHR | |
| SCHEMBL28986001 | 0.78 | HPGD (0.60) | HRH1HPGDSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL5146718 | 0.78 | HRH1 (0.71) | HRH1HPGDSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL11033196 | 0.78 | HPGD (0.81) | HRH1HPGDSMN1; SMN2TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983623-A | Prolyl endopeptidase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |