Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.40 |
| ▸ | WNT3A | P56704 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775138 | 0.85 | HPGD (0.48) | ALDH1A1RAB9AHPGDL3MBTL1KDM4E | |
| SCHEMBL9775196 | 0.81 | ALDH1A1 (0.53) | ALDH1A1RAB9AHPGDL3MBTL1MAPK1 | |
| SCHEMBL14732971 | 0.75 | CTNNB1 (0.61) | ALDH1A1RAB9AHPGDCTNNB1WNT3A | |
| SCHEMBL21101969 | 0.74 | ALDH1A1 (0.45) | ALDH1A1RAB9AHPGDL3MBTL1MAPK1 | |
| SCHEMBL5168941 | 0.73 | ACHE (0.46) | ALDH1A1RAB9AMAPK1HTTPOLB | |
| SCHEMBL21102257 | 0.72 | ALDH1A1 (0.58) | ALDH1A1HPGDL3MBTL1MAPK1 | |
| SCHEMBL31304722 | 0.72 | HDAC1 (0.47) | ALDH1A1RAB9AHPGDL3MBTL1MAPK1 | |
| SCHEMBL2776945 | 0.71 | MAPT (0.53) | ALDH1A1HPGDL3MBTL1MAPK1HTT | |
| SCHEMBL3645531 | 0.71 | ALDH1A1 (0.47) | ALDH1A1RAB9AHPGDL3MBTL1MAPK1 | |
| SCHEMBL6757360 | 0.71 | HDAC3 (0.55) | ALDH1A1KDM4ECTNNB1WNT3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075339-A | Antiinflammatory agents, antiallergens | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-24 | — | — | US | claimed |
| US-5075339-A | Antiinflammatory agents, antiallergens | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-4948813-A | Benzylketone phospholipase A2 inhibitors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-14 | — | — | US | disclosed |