Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775192 | 0.85 | KAT6A (0.47) | HPGDKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9775156 | 0.80 | RAB9A (0.70) | HPGDNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL14732971 | 0.78 | CTNNB1 (0.61) | HPGDNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL9775143 | 0.77 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1L3MBTL1LMNA | |
| SCHEMBL15979729 | 0.76 | PKM (0.62) | NPC1RAB9AMEN1KMT2ACTNNB1 | |
| SCHEMBL17131550 | 0.74 | HPGD (0.53) | HPGDKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL417732 | 0.74 | ALDH1A1 (0.70) | HPGDKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL6757360 | 0.74 | HDAC3 (0.55) | KDM4EALDH1A1MEN1KMT2ACTNNB1 | |
| SCHEMBL30089515 | 0.73 | CTNNB1 (0.68) | HPGDNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL9775220 | 0.72 | HSP90AA1 (0.60) | HPGDKDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075339-A | Antiinflammatory agents, antiallergens | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-24 | — | — | US | claimed |
| US-5075339-A | Antiinflammatory agents, antiallergens | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-4948813-A | Benzylketone phospholipase A2 inhibitors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-14 | — | — | US | disclosed |