Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716228 | 0.98 | ACE (0.55) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL10747717 | 0.98 | ACE (0.55) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL5364563 | 0.98 | ACE (0.55) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL5716232 | 0.98 | ACE (0.55) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL4404273 | 0.83 | ACE (0.53) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL9773233 | 0.82 | CTSL (0.54) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL9592654 | 0.82 | CTSL (0.54) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL9775205 | 0.81 | ACE (0.44) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL9256682 | 0.80 | CTSL (0.54) | ACEKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL18829369 | 0.79 | CHRM2 (0.45) | ACEKMT2AMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068242-A | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE FOR PSYCHOTROPIC ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |