Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775578 | 1.00 | AKR1C1 (0.44) | AKR1C1CES1ALDH1A1MEN1KMT2A | |
| SCHEMBL9775612 | 0.79 | MAPT (0.46) | CES1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9775608 | 0.79 | MAPT (0.46) | CES1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10363546 | 0.78 | AKR1C3 (0.52) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL9775586 | 0.78 | AKR1C3 (0.52) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL11513786 | 0.77 | MTNR1A (0.54) | AKR1C1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10006566 | 0.77 | MTNR1A (0.54) | AKR1C1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7664129 | 0.75 | GLA (0.38) | AKR1C1CES1ALDH1A1MEN1KMT2A | |
| SCHEMBL11038550 | 0.75 | RAB9A (0.51) | AKR1C1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4866101 | 0.74 | CES1 (0.54) | CES1ALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987140-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4925859-A | Novel 4-hydroxy-3-pyridine-carboxamides useful for treating inflammation and rheumatism | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |