SCHEMBL977562

SCHEMBL977562

CO[Si](C)(C)CNCCN

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.41
CA6 P23280 4/20 0.41
CA7 P43166 4/20 0.41
CA9 Q16790 4/20 0.41
CA14 Q9ULX7 4/20 0.41
CA5B Q9Y2D0 4/20 0.41
MEN1 O00255 2/20 0.41
RECQL P46063 2/20 0.41
KMT2A Q03164 2/20 0.41
CA2 P00918 3/20 0.39
CA4 P22748 3/20 0.39
CA5A P35218 3/20 0.39
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CA3 P07451 2/20 0.39
ALOX15 P16050 2/20 0.39
CA1 P00915 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2428717 0.83 CA12 (0.43) CA12CA6CA7CA9CA14
SCHEMBL4598957 0.82
SCHEMBL975755 0.81 CA12 (0.41) CA12CA6CA7CA9CA14
SCHEMBL8381466 0.80
SCHEMBL21496029 0.79 TSHR (0.44) CA12CA7CA14CA2ALOX15
SCHEMBL14732727 0.79 CA12 (0.46) CA12CA6CA7CA9CA14
SCHEMBL29314583 0.79 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL131935 0.78 CA12 (0.43) CA12CA6CA7CA9CA14
SCHEMBL21496059 0.78
SCHEMBL978206 0.77 CA12 (0.46) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3543246-B1 COMPOSITION CONTAINING ORGANIC SILICON COMPOUND AND PAINT AND ADHESIVE CONTAINING SAID COMPOSITION SHINETSU CHEMICAL CO (JP) 2024-05-15 EP disclosed
US-10995106-B2 Composition containing organic silicon compound and paint and adhesive containing said composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-05-04 US disclosed
CN-111989348-A Polymer having reactive silicon-containing group and method for producing same 信越化学工业株式会社 2020-11-24 CN disclosed
US-20200048284-A1 COMPOSITION CONTAINING ORGANIC SILICON COMPOUND AND PAINT AND ADHESIVE CONTAINING SAID COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 US disclosed
EP-3543246-A1 COMPOSITION CONTAINING ORGANIC SILICON COMPOUND AND PAINT AND ADHESIVE CONTAINING SAID COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2019-09-25 EP disclosed
EP-2289898-B1 Melamine-functional organosilicon compound and making method SHINETSU CHEMICAL CO (JP) 2017-05-03 EP disclosed
US-8314264-B2 Photopolymerizable functional radical-containing organosilicon compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-11-20 US disclosed
US-8263766-B2 Melamine-functional organosilicon compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-09-11 US disclosed
EP-2289898-A1 Melamine-Functional organosilicon compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2011-03-02 EP disclosed
US-20110003989-A1 MELAMINE-FUNCTIONAL ORGANOSILICON COMPOUND AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-01-06 US disclosed
US-7737242-B2 Crosslinkable siloxane urea copolymers WACKER CHEMIE AG (DE) 2010-06-15 US disclosed
US-7645516-B2 Cross-linkable siloxane urea copolymers WACKER CHEMIE AG (DE) 2010-01-12 US disclosed
EP-1784442-B1 CROSSLINKABLE SILOXANE UREA COPOLYMERS WACKER CHEMIE AG (DE) 2009-10-07 EP disclosed
US-20090143496-A1 CROSSLINKABLE SILOXANE-UREA COPOLYMERS WACKER CHEMIE AG (DE) 2009-06-04 US disclosed
US-20080045671-A1 Cross-Linkable Siloxane Urea Copolymers WACKER CHEMIE AG (DE) 2008-02-21 US disclosed
US-20070232772-A1 Crosslinkable Siloxane Urea Copolymers WACKER CHEMIE AG (DE) 2007-10-04 US disclosed
EP-1817364-A2 CROSSLINKABLE SILOXANE-UREA COPOLYMERS Wacker Chemie AG (DE) 2007-08-15 EP disclosed
EP-1771496-A1 CROSS-LINKABLE SILOXANE UREA COPOLYMERS Wacker Chemie AG (DE) 2007-04-11 EP disclosed
WO-2006058656-A2 CROSSLINKABLE SILOXANE-UREA COPOLYMERS WACKER CHEMIE AG (DE) 2006-06-08 WO disclosed
WO-2006010486-A1 CROSS-LINKABLE SILOXANE UREA COPOLYMERS WACKER CHEMIE AG (DE) 2006-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003989-A1 MELAMINE-FUNCTIONAL ORGANOSILICON COMPOUND AND MAKING METHOD MEN1, MSH6, PRMT6 CA12 330/4885CA6 62/4885CA7 265/4885
US-20090143496-A1 CROSSLINKABLE SILOXANE-UREA COPOLYMERS CCNT1, PCNA, RAD1 CA12 3198/4885CA6 3046/4885CA7 3812/4885
US-10995106-B2 Composition containing organic silicon compound and paint and adhesive containing said composition OR10J3, ASH2L, SOST CA12 1981/4885CA6 1938/4885CA7 1634/4885
US-20200048284-A1 COMPOSITION CONTAINING ORGANIC SILICON COMPOUND AND PAINT AND ADHESIVE CONTAINING SAID COMPOSITION OR10J3, ASH2L, SOST CA12 1981/4885CA6 1938/4885CA7 1634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.