Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775660 | 1.00 | CES1 (0.46) | CES1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7094138 | 0.87 | PTGS2 (0.44) | — | |
| SCHEMBL7093579 | 0.87 | PTGS2 (0.44) | — | |
| SCHEMBL9775663 | 0.81 | RAB9A (0.45) | CES1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9775669 | 0.81 | ALDH1A1 (0.45) | CES1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9775673 | 0.81 | ALDH1A1 (0.45) | CES1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9775659 | 0.81 | RAB9A (0.45) | CES1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7090172 | 0.79 | CES1 (0.44) | CES1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7090169 | 0.79 | CES1 (0.44) | CES1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7092171 | 0.77 | PTGS2 (0.49) | CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987140-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4925859-A | Novel 4-hydroxy-3-pyridine-carboxamides useful for treating inflammation and rheumatism | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |