Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615008 | 0.78 | ALDH1A1 (0.60) | CYP1A2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9775626 | 0.75 | RAB9A (0.49) | CYP1A2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL3278951 | 0.74 | CYP1A2 (0.73) | CYP1A2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5206561 | 0.74 | CYP1A2 (1.00) | CYP1A2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4636379 | 0.74 | NPC1 (0.73) | CYP1A2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9775624 | 0.73 | RAB9A (0.54) | CYP1A2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9775591 | 0.73 | RAB9A (0.46) | CYP1A2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL995829 | 0.72 | NPC1 (1.00) | CYP1A2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11862403 | 0.71 | MEN1 (0.61) | CYP1A2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL1897970 | 0.71 | NPC1 (1.00) | CYP1A2ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987140-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4925859-A | Novel 4-hydroxy-3-pyridine-carboxamides useful for treating inflammation and rheumatism | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |