Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | EBP | Q15125 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18760165 | 0.84 | NPC1 (0.67) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9033333 | 0.78 | KMT2A (0.66) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL27877058 | 0.78 | SIGMAR1 (0.64) | MEN1KMT2AEBPSIGMAR1TP53 | |
| SCHEMBL7359486 | 0.76 | NPC1 (0.53) | NPC1RAB9ALMNASMN1; SMN2NPSR1 | |
| SCHEMBL11837939 | 0.75 | LMNA (0.61) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL12462709 | 0.75 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPTLMNATP53 | |
| SCHEMBL9027195 | 0.75 | SIGMAR1 (0.54) | ALDH1A1EBPSIGMAR1TMEM97SMN1; SMN2 | |
| SCHEMBL8075010 | 0.74 | SIGMAR1 (0.89) | EBPSIGMAR1TMEM97 | |
| SCHEMBL27334030 | 0.74 | SIGMAR1 (0.56) | ALDH1A1MEN1KMT2AEBPSIGMAR1 | |
| SCHEMBL9129577 | 0.74 | MEN1 (0.60) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3246286-A | — | — | None | — | — | JP | disclosed |
| JP-H03246286-A | PIPERAZINE DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1991-11-01 | — | — | JP | disclosed |