Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775925 | 0.89 | TOP2A (0.56) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9775934 | 0.88 | KMT2A (0.46) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9527325 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8941979 | 0.86 | DPP4 (0.50) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL8942162 | 0.86 | DPP4 (0.56) | KDM4EALDH1A1HSD17B10POLBDPP4 | |
| SCHEMBL8942245 | 0.85 | DPP4 (0.49) | KDM4EALDH1A1HSD17B10POLBDPP4 | |
| Water SCHEMBL8942213 | 0.85 | DPP4 (0.55) | KDM4EALDH1A1HSD17B10POLBDPP4 | |
| SCHEMBL9775887 | 0.85 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10HRH3 | |
| SCHEMBL9776017 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL6609141 | 0.84 | DPP4 (0.54) | KDM4EALDH1A1HPGDHSD17B10DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004745-A | Benzo[1,8]naphthyridine derivatives, their preparation and the compositions which contain them | LABORATOIRE ROGER BELLON (FR) | 1991-04-02 | — | — | US | disclosed |