Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156733 | 0.78 | S1PR1 (0.46) | TSHRSMN1; SMN2S1PR2S1PR4S1PR1 | |
| SCHEMBL9776046 | 0.77 | HPGD (0.46) | TSHRFDPSSMN1; SMN2CA1CA2 | |
| SCHEMBL9776042 | 0.77 | HPGD (0.46) | TSHRFDPSSMN1; SMN2CA1CA2 | |
| SCHEMBL9776156 | 0.76 | ARG1 (0.47) | TSHRFDPSSMN1; SMN2SIGMAR1KMT2A | |
| SCHEMBL6009477 | 0.68 | SIGMAR1 (0.37) | FDPSSMN1; SMN2SIGMAR1 | |
| SCHEMBL9776134 | 0.68 | SIGMAR1 (0.41) | TSHRFDPSSIGMAR1S1PR4S1PR1 | |
| SCHEMBL9776023 | 0.68 | SIGMAR1 (0.41) | TSHRFDPSSMN1; SMN2SIGMAR1S1PR4 | |
| SCHEMBL14896852 | 0.68 | TSHR (0.40) | TSHRSMN1; SMN2S1PR2S1PR4S1PR1 | |
| SCHEMBL28256955 | 0.68 | ALOX15 (0.47) | TSHRSMN1; SMN2S1PR2S1PR4S1PR1 | |
| SCHEMBL2163768 | 0.67 | FDPS (0.51) | TSHRFDPSSMN1; SMN2SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994617-A | Analgesics | JOUVEINAL S.A. (FR) | 1991-02-19 | — | — | US | disclosed |