Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445015 | 0.84 | TP53 (0.58) | SRD5A2RAB9ANPC1MAPK13MAPK12 | |
| SCHEMBL10396989 | 0.84 | SRD5A2 (0.47) | SRD5A2RAB9ACES2CES1NPC1 | |
| SCHEMBL27384436 | 0.82 | GAA (0.59) | SRD5A2RAB9ACES2HTTMEN1 | |
| SCHEMBL38533242 | 0.81 | AKR1C3 (0.66) | SRD5A2RAB9ACES2CES1NPC1 | |
| SCHEMBL8362275 | 0.81 | SRD5A2 (0.55) | SRD5A2RAB9ACES2CES1NPC1 | |
| SCHEMBL11751786 | 0.81 | AKR1C3 (0.66) | SRD5A2RAB9ACES2CES1NPC1 | |
| SCHEMBL28762149 | 0.81 | SRD5A2 (0.44) | SRD5A2RAB9ACES2CES1NPC1 | |
| SCHEMBL1584375 | 0.80 | KMT2A (0.56) | RAB9ANPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL25850063 | 0.80 | TAS2R14 (0.52) | SRD5A2RAB9ACES2NPC1ALDH1A1 | |
| SCHEMBL29530541 | 0.80 | AKR1C3 (0.69) | SRD5A2CES2CES1MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017730-A | Process of preparing bis (trifluoromethylphenyl) methanol | CENTRAL GLASS COMPANY, LIMITED (JP) | 1991-05-21 | — | — | US | disclosed |