SCHEMBL25850063

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28672497	0.85	TDP1 (0.58)	PTGS2SRD5A2NPC1RAB9AGLA
	SCHEMBL12360588	0.83	PTGS2 (0.47)	PTGS2CNR2CES2CNR1ALDH1A1
	SCHEMBL9537242	0.82	KDM4E (0.62)	TAS2R14SRD5A2CNR2P2RX1CES2
	SCHEMBL5992479	0.82	CNR2 (0.55)	SRD5A2CNR2GAAP2RX1CES2
	SCHEMBL30070755	0.82	CNR2 (0.55)	SRD5A2CNR2GAAP2RX1CES2
	SCHEMBL29941444	0.82	SRD5A2 (0.51)	SRD5A2CNR2P2RX1CES2CNR1
	SCHEMBL3660770	0.82	SRD5A2 (0.51)	SRD5A2CNR2P2RX1CES2CNR1
	SCHEMBL3486347	0.82	MAPT (0.61)	SRD5A2CNR2GAAP2RX1CES2
	SCHEMBL710431	0.81	TAS2R14 (0.59)	TAS2R14CES2HPGDKDM4EUSP2
	SCHEMBL27353325	0.81	GLA (0.55)	SRD5A2CNR2P2RX1CES2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.