Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415149 | 0.77 | HTR2A (0.36) | LMNAKDM4EALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9767442 | 0.76 | CSNK1E (0.37) | LMNAKDM4ERIPK1ALDH1A1HTR2A | |
| SCHEMBL9776466 | 0.74 | HPGD (0.40) | LMNAALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL18083240 | 0.74 | HSP90AA1 (0.37) | LMNAALDH1A1TSHRCYP2C19MEN1 | |
| SCHEMBL27988263 | 0.73 | RIPK1 (0.41) | LMNAADRA2CADRA2AHIF1ARIPK1 | |
| SCHEMBL6841869 | 0.72 | RIPK1 (0.39) | LMNAKDM4ERIPK1ALDH1A1SLC6A4 | |
| SCHEMBL9767783 | 0.70 | LMNA (0.39) | LMNACYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL23221180 | 0.69 | KDM4E (0.56) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8287058 | 0.69 | KDM4E (0.56) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL3245155 | 0.69 | KDM4E (0.56) | LMNAADRA2CKDM4EADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996345-A | Difluoroketones from difluoroacylsilanes | PFIZER INC. (US) | 1991-02-26 | — | — | US | disclosed |