Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776328 | 0.76 | LMNA (0.37) | RIPK1ALDH1A1KDM4EHTR2ALMNA | |
| SCHEMBL9776400 | 0.74 | FAAH (0.43) | ALDH1A1ASAH1SMPD2SMPD1ACER2 | |
| Propene SCHEMBL28101476 | 0.71 | RIPK1 (0.51) | CSNK1ERIPK1NAAAALDH1A1KDM4E | |
| SCHEMBL19520149 | 0.71 | CSNK1E (0.40) | CSNK1ENAAAALDH1A1LMNA | |
| SCHEMBL4635969 | 0.71 | SIGMAR1 (0.41) | CSNK1ENAAAALDH1A1KDM4EHTR2A | |
| SCHEMBL317208 | 0.69 | LMNA (0.61) | CSNK1ERIPK1NAAAALDH1A1KDM4E | |
| SCHEMBL28218362 | 0.69 | LMNA (0.61) | CSNK1ERIPK1NAAAALDH1A1KDM4E | |
| SCHEMBL11896274 | 0.69 | HTR2A (0.41) | CSNK1ENAAAALDH1A1HTR2AASAH1 | |
| SCHEMBL17183673 | 0.69 | HTR2A (0.41) | CSNK1ENAAAALDH1A1HTR2AASAH1 | |
| SCHEMBL17183733 | 0.69 | HTR2A (0.41) | CSNK1ENAAAALDH1A1HTR2AASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057626-A | Difluoroketones from difluoroacylsilanes | PFIZER INC. (US) | 1991-10-15 | — | — | US | disclosed |
| US-4996345-A | Difluoroketones from difluoroacylsilanes | PFIZER INC. (US) | 1991-02-26 | — | — | US | disclosed |