Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9514172 | 0.79 | ALDH1A1 (0.71) | ALDH1A1TSHRSMN1; SMN2ALOX15NR4A1 | |
| SCHEMBL12742272 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TSHRSMN1; SMN2ALOX15NR4A1 | |
| SCHEMBL11575597 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TSHRSMN1; SMN2ALOX15NR4A1 | |
| Hydrochloric Acid SCHEMBL9778047 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHRSMN1; SMN2ALOX15NR4A1 | |
| SCHEMBL801233 | 0.76 | ALDH1A1 (0.72) | ALDH1A1TSHRSMN1; SMN2ALOX15NR4A1 | |
| SCHEMBL11483697 | 0.76 | AOC3 (0.62) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL13569328 | 0.76 | AOC3 (0.62) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL339492 | 0.75 | ALOX15 (0.81) | ALDH1A1TSHRSMN1; SMN2ALOX15NR4A1 | |
| SCHEMBL6831673 | 0.74 | ALDH1A1 (0.64) | ALDH1A1TSHRSMN1; SMN2ALOX15NR4A1 | |
| SCHEMBL9323967 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TSHRSMN1; SMN2ALOX15NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |