Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656832 | 0.88 | LMNA (0.67) | ALDH1A1TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL15942681 | 0.86 | ALOX15 (0.66) | ALDH1A1TSHRALOX15SMN1; SMN2FFAR1 | |
| Hydrochloric Acid SCHEMBL3246059 | 0.86 | LMNA (0.65) | ALDH1A1TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL27906819 | 0.86 | LMNA (0.65) | ALDH1A1TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL9807246 | 0.84 | PPARD (0.47) | ALDH1A1TSHRLMNAFFAR1PPARG | |
| SCHEMBL7874508 | 0.84 | ALOX15 (0.58) | ALDH1A1TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL6026352 | 0.83 | THRA (0.55) | ALDH1A1TSHRLMNAALOX15SMN1; SMN2 | |
| SCHEMBL9807230 | 0.83 | PPARD (0.57) | PPARGPPARDPPARA | |
| SCHEMBL9321566 | 0.83 | GAA (0.54) | ALDH1A1FFAR1PPARGPPARDPPARA | |
| SCHEMBL6831673 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRALOX15SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322348-B1 | Acidically non-stable anchoring groups for solid-phase peptide amide synthesis | HOECHST AG (DE) | 1994-02-02 | — | — | EP | disclosed |
| US-5124478-A | ACID-LABILE ANCHOR GROUPS FOR THE SYNTHESIS OF PEPTIDE AMIDES BY A SOLID-PHASE METHOD | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-23 | — | — | US | disclosed |
| EP-0287882-B1 | SYNTHESIS OF PEPTIDAMIDES BY THE SOLID PHASE METHOD USING ANCHOR GROUPS UNSTABLE AS TO ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-02 | — | — | EP | disclosed |
| US-4922015-A | Synthesis of peptide amides by means of a solid phase method using acid-labile anchoring groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| EP-0322348-A2 | Acidically non-stable anchoring groups for solid-phase peptide amide synthesis | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-28 | — | — | EP | disclosed |
| EP-0287882-A1 | Synthesis of peptidamides by the solid phase method using anchor groups unstable as to acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-26 | — | — | EP | disclosed |