Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592696 | 0.88 | HTT (0.50) | ALDH1A1MAPTKAT6APKMMAPK1 | |
| SCHEMBL9777991 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTNPSR1POLBMEN1 | |
| SCHEMBL9778006 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAPTKAT6APKMNPSR1 | |
| SCHEMBL9777957 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MAPTKAT6ANPSR1CA1 | |
| SCHEMBL9778075 | 0.82 | FABP4 (0.54) | ALDH1A1MAPTHTTNPSR1RAB9A | |
| SCHEMBL9777976 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTNPSR1POLBCA1 | |
| SCHEMBL9777971 | 0.81 | TBXA2R (0.59) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL9777950 | 0.81 | TSHR (0.59) | ALDH1A1MAPTNPSR1POLBNPC1 | |
| SCHEMBL9777982 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTNPSR1POLBCA1 | |
| SCHEMBL9778050 | 0.73 | GAA (0.48) | ALDH1A1MAPTNPSR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |