Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899494 | 0.88 | ALDH1A1 (0.59) | TSHRALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9777991 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTPOLBLMNAFFAR1 | |
| SCHEMBL9778006 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNANPSR1MEP1B | |
| SCHEMBL5899460 | 0.85 | TSHR (0.61) | TSHRALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9777957 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTFFAR1NPSR1TBXA2R | |
| SCHEMBL9777976 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBLMNAFFAR1 | |
| SCHEMBL9777971 | 0.84 | TBXA2R (0.59) | ALDH1A1MAPTNPSR1TBXA2RTBXAS1 | |
| SCHEMBL23014131 | 0.81 | ALDH1A1 (0.57) | TSHRALDH1A1MEP1B | |
| SCHEMBL9777983 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9777982 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |