Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778021 | 0.89 | TBXA2R (0.62) | MMP2MMP9MMP14ADAM17MMP1 | |
| SCHEMBL9777989 | 0.88 | TBXA2R (0.49) | MMP1TBXA2RTBXAS1ALDH1A1SGMS1 | |
| SCHEMBL9765316 | 0.88 | ALDH1A1 (0.54) | MMP2MMP9MMP14ADAM17MMP1 | |
| SCHEMBL9778031 | 0.85 | SMN1; SMN2 (0.58) | ALDH1A1CA1CA2HSP90AA1HSP90AB1 | |
| SCHEMBL7302709 | 0.84 | ITGB3 (0.49) | TBXA2RTBXAS1ALDH1A1IDO1HSP90AA1 | |
| SCHEMBL24590667 | 0.78 | CA1 (0.56) | ALDH1A1LMNACA1CA2SMN1; SMN2 | |
| SCHEMBL28526568 | 0.78 | CA1 (0.57) | ALDH1A1LMNACA1CA2TSHR | |
| SCHEMBL11342321 | 0.78 | TBXA2R (0.79) | MMP2MMP9MMP14ADAM17MMP1 | |
| SCHEMBL9512068 | 0.78 | TBXA2R (0.63) | MMP2MMP9MMP14ADAM17MMP1 | |
| SCHEMBL10701921 | 0.77 | ALDH1A1 (0.56) | TBXA2RTBXAS1ALDH1A1IDO1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |