Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778021 | 0.89 | TBXA2R (0.62) | TBXA2RTBXAS1ALDH1A1MMP1GAA | |
| SCHEMBL9510767 | 0.88 | ALDH1A1 (0.54) | TBXA2RTBXAS1ALDH1A1SGMS1MMP1 | |
| SCHEMBL9778015 | 0.88 | MMP2 (0.49) | TBXA2RTBXAS1ALDH1A1SGMS1MMP1 | |
| SCHEMBL9778016 | 0.85 | SMN1; SMN2 (0.58) | ALDH1A1GAAADRB3CYP2C9CYP2C19 | |
| SCHEMBL9777956 | 0.85 | MEN1 (0.46) | TBXA2RTBXAS1ALDH1A1SGMS1MMP1 | |
| SCHEMBL10703387 | 0.85 | ALDH1A1 (0.51) | TBXA2RTBXAS1ALDH1A1SGMS1MMP1 | |
| SCHEMBL9777945 | 0.84 | ADRB2 (0.48) | ALDH1A1SGMS1MMP1GAAADRB3 | |
| SCHEMBL7302709 | 0.84 | ITGB3 (0.49) | TBXA2RTBXAS1ALDH1A1IDO1HSP90AA1 | |
| SCHEMBL9777974 | 0.83 | TBXA2R (0.45) | TBXA2RTBXAS1ALDH1A1SGMS1MMP1 | |
| SCHEMBL2840998 | 0.83 | PGR (0.60) | ALDH1A1MMP1GAACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |