Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301011 | 0.89 | POLB (0.57) | ALDH1A1POLBPLAUHPNHSP90AA1 | |
| Hydrochloric Acid SCHEMBL9265744 | 0.89 | POLB (0.56) | ALDH1A1TMPRSS6POLBPLAUHPN | |
| SCHEMBL9778021 | 0.85 | TBXA2R (0.62) | TBXA2RTBXAS1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL9777989 | 0.84 | TBXA2R (0.49) | TBXA2RTBXAS1ALDH1A1IDO1HSP90AA1 | |
| SCHEMBL9778015 | 0.84 | MMP2 (0.49) | TBXA2RTBXAS1ALDH1A1IDO1HSP90AA1 | |
| SCHEMBL7302514 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BTBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL7298011 | 0.82 | ITGB3 (0.57) | ITGB3ITGA2BALDH1A1TSHRF10 | |
| SCHEMBL7566223 | 0.81 | TMPRSS6 (0.48) | ALDH1A1TMPRSS6PLAUHPNF2 | |
| SCHEMBL7566215 | 0.81 | TMPRSS6 (0.48) | TMPRSS6PLAUHPNF2F10 | |
| SCHEMBL7292860 | 0.80 | TBXA2R (0.72) | ITGB3ITGA2BTBXA2RTBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |
| US-5399585-A | Anitcoagulants, antiinflammatory, antitumor | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | disclosed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5084466-A | Anticoagulants, antiinflammatory agents, atheriosclerosis and antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1992-01-28 | — | — | US | disclosed |