Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778031 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL9777951 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL9777989 | 0.85 | TBXA2R (0.49) | SMN1; SMN2TSHRGAANPSR1ALDH1A1 | |
| SCHEMBL9313088 | 0.81 | TSHR (0.62) | SMN1; SMN2TSHR | |
| SCHEMBL9129860 | 0.81 | TSHR (0.65) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL9777945 | 0.80 | ADRB2 (0.48) | SMN1; SMN2GAANPSR1ALDH1A1TP53 | |
| SCHEMBL9765332 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL9510518 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRGAANPSR1POLB | |
| SCHEMBL28910541 | 0.79 | MAPT (0.58) | SMN1; SMN2TSHRGAANPSR1ALDH1A1 | |
| SCHEMBL7911907 | 0.78 | ALDH1A1 (0.59) | SMN1; SMN2TSHRGAANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |