Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGFR | P43088 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339850 | 0.88 | SMN1; SMN2 (0.38) | PTGS2PTGS1KMT2AMAPTALDH1A1 | |
| SCHEMBL9341673 | 0.84 | SMN1; SMN2 (0.39) | PTGS2PTGS1TP53TBXA2RPTGER3 | |
| SCHEMBL10585548 | 0.83 | PTGER3 (0.37) | PTGS2PTGS1TBXA2RPTGER3PTGER2 | |
| SCHEMBL9338556 | 0.82 | SMN1; SMN2 (0.42) | PTGS2PTGS1MEN1KMT2AMAPT | |
| SCHEMBL10499047 | 0.79 | THRA (0.44) | MEN1KMT2ACYP1A2 | |
| SCHEMBL10497881 | 0.79 | THRA (0.47) | MEN1KMT2ACYP1A2 | |
| SCHEMBL9337936 | 0.76 | SLC16A3 (0.38) | PTGS2PTGS1TBXA2RPTGER3PTGER2 | |
| SCHEMBL9338280 | 0.76 | SMN1; SMN2 (0.42) | PTGS2PTGS1TBXA2RPTGER3PTGER2 | |
| SCHEMBL9338260 | 0.75 | SLC16A3 (0.40) | CYP1A2SMN1; SMN2 | |
| SCHEMBL9338419 | 0.75 | SMN1; SMN2 (0.36) | PTGS2PTGS1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |