Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779151 | 0.89 | HTT (0.54) | PGRNR3C1ARESR2HTT | |
| SCHEMBL9778897 | 0.87 | NR3C1 (0.55) | PGRNR3C1ARESR2L3MBTL1 | |
| SCHEMBL9778780 | 0.86 | NR3C1 (0.53) | PGRNR3C1ARESR2L3MBTL1 | |
| SCHEMBL9778880 | 0.84 | PGR (0.59) | PGRNR3C1ARESR2HTT | |
| SCHEMBL5669904 | 0.80 | MAOB (0.47) | PGRNR3C1ARESR2L3MBTL1 | |
| SCHEMBL9779035 | 0.78 | PTGES2 (0.42) | PGRNR3C1ARESR2HTT | |
| SCHEMBL9778961 | 0.78 | PTGES2 (0.52) | HTTTDP1L3MBTL1ABCC9ABCC8 | |
| SCHEMBL9779282 | 0.77 | HTT (0.47) | PGRNR3C1ARESR2HTT | |
| SCHEMBL9779001 | 0.76 | PTGES2 (0.54) | PGRNR3C1ARESR2HTT | |
| SCHEMBL8855050 | 0.76 | NR3C1 (0.57) | PGRNR3C1ARESR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066409-A | Novel aryl ether sulfones | THE DOW CHEMICAL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |