Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779171 | 0.89 | PGR (0.43) | HTTTDP1L3MBTL1NR3C1PGR | |
| SCHEMBL9778977 | 0.88 | NR3C1 (0.57) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL8855050 | 0.88 | NR3C1 (0.57) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL9778945 | 0.86 | NR3C1 (0.56) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL5669904 | 0.82 | MAOB (0.47) | L3MBTL1SMN1; SMN2NR3C1PGRAR | |
| SCHEMBL10709703 | 0.81 | HTT (0.60) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL9778880 | 0.80 | PGR (0.59) | HTTTDP1L3MBTL1NR3C1PGR | |
| SCHEMBL9779047 | 0.79 | HTT (0.54) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL9779083 | 0.78 | HTT (0.56) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL9778897 | 0.76 | NR3C1 (0.55) | L3MBTL1NR3C1PGRARESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066409-A | Novel aryl ether sulfones | THE DOW CHEMICAL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |