Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780319 | 0.81 | RAB9A (0.57) | PKMBRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9780195 | 0.81 | HTR2C (0.45) | HTR2CHTR2BPKMGLAMAPT | |
| Hydrochloric Acid SCHEMBL9780231 | 0.81 | RAB9A (0.60) | PKMBRD4ALDH1A1 | |
| SCHEMBL9780219 | 0.80 | L3MBTL1 (0.46) | HTR2CHTR2BPKMGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9780247 | 0.78 | HTR2C (0.66) | HTR2CHTR2BPKMMAPT | |
| Hydrochloric Acid SCHEMBL9780252 | 0.78 | HTR2C (0.62) | HTR2CHTR2BPKMMAPTGAA | |
| Iodide SCHEMBL9780273 | 0.78 | BRD4 (0.42) | HTR2CHTR2BPKMMAPTGAA | |
| Iodide SCHEMBL9780276 | 0.78 | BRD4 (0.42) | HTR2CHTR2BPKMMAPTGAA | |
| SCHEMBL2266915 | 0.76 | PKM (0.73) | PKMGLAMAPTALDH1A1 | |
| SCHEMBL3824011 | 0.75 | MAPT (0.69) | PKMGLAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030631-A | Hypotensive, bronchodilator agents | SCHERING CORPORATION (US) | 1991-07-09 | — | — | US | claimed |
| US-5030631-A | Hypotensive, bronchodilator agents | SCHERING CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |