Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734549 | 0.80 | CA1 (0.48) | KCNA5TDP1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL9780181 | 0.78 | KCNA5 (0.38) | KCNA5USP2F2F10PRSS1 | |
| SCHEMBL9733728 | 0.78 | ALDH1A1 (0.51) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8535929 | 0.78 | KCNA5 (0.49) | KCNA5USP2TDP1MAPTALDH1A1 | |
| SCHEMBL8820375 | 0.77 | MAPT (0.56) | TDP1MAPTRAB9AGAAALDH1A1 | |
| SCHEMBL9735344 | 0.76 | PLK1 (0.45) | MAPTGAAALDH1A1LMNAMEN1 | |
| SCHEMBL9057225 | 0.75 | HSD17B10 (0.50) | TDP1MAPTGAAALDH1A1L3MBTL1 | |
| SCHEMBL9780324 | 0.73 | ALDH1A1 (0.40) | KCNA5F2F10PRSS1MAPT | |
| SCHEMBL3652597 | 0.72 | CA1 (0.55) | TDP1MAPTRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL10793688 | 0.72 | ALDH1A1 (0.38) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990526-A | Skin disorders, antiallergens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1991-02-05 | — | — | US | disclosed |