Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631320 | 0.83 | TDP1 (0.53) | MAPTPOLBMAPK1CES1RAB9A | |
| SCHEMBL9781450 | 0.81 | LMNA (0.52) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2852910 | 0.80 | RAB9A (0.62) | MAPTPOLBMEN1KMT2ARAB9A | |
| SCHEMBL24421736 | 0.80 | MAPK1 (0.55) | MAPK1CES1RAB9ANPC1TP53 | |
| SCHEMBL9734549 | 0.80 | CA1 (0.48) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL4710743 | 0.79 | GAA (0.52) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL9733728 | 0.78 | ALDH1A1 (0.51) | MEN1KMT2ACES1HTTLMNA | |
| SCHEMBL9780181 | 0.78 | KCNA5 (0.38) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL28806881 | 0.78 | ADRB2 (0.52) | MAPTPOLBMAPK1MEN1KMT2A | |
| SCHEMBL2848793 | 0.78 | MAPT (0.54) | MAPTPOLBMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9040601-A | — | — | None | — | — | JP | disclosed |
| JP-H0940601-A | PRODUCTION OF OPTICALLY ACTIVE KETONE DERIVATIVE AND THE SAME | NIPPON SODA CO LTD | 1997-02-10 | — | — | JP | disclosed |
| JP-H00940601-A | — | — | 0001-01-01 | — | — | JP | disclosed |